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Alopecia

DEFINITION

Alopecia is the medical term for baldness, but can refer to all sorts of hair loss including that from heredity, medications, or medical conditions. While we generally think hair loss affects men, it can also affect women and children. Hair loss can be very traumatizing. It can affect how you feel and interact in social situations. Normally, the hairs on your head go through cycles when they grow (anagen phase) and when they rest (telogen phase). Each hair independently goes through these stages, with about 90% of hairs in anagen stage most of the time. Anagen phase lasts about two to three years. Telogen phase lasts three to four months and ends with the hair falling out. After the hair falls out, a new young hair begins to grow in its place. Out of the 100,000 hairs on the head, it is normal to shed 50 to 100 hairs per day which should not make a visible difference. There are many types of baldness. Perhaps the most recognized is “male pattern baldness” (androgenetic alopecia) though this can affect women as well. In this type of hair loss, hair growth time becomes shorter and thinner as a result of androgens (hormones). They also become less deeply rooted and fall out more easily. Men with this type of hair loss generally begin losing their hair in their teens to twenties beginning at the temples and top of the head. In women, this type of hair loss is characterized by thinning in the front, sides and top of the head. Cicatricial alopecia is a permanent hair loss which results from scarring of the hair follicles due to inflammation from conditions like lupus or lichen planus which prevent further hair growth. Sometimes people with this type of hair loss with also have itching or scalp pain. Alopecia areata is a type of patchy hair loss due to some sort of autoimmune disease, though the exact cause is unknown. This type of hair loss usually occurs in quarter-sized round patches which can even occur in the eyebrows and facial hair. Usually, the patchy areas will grow back over time and with the help of medications but the cycle of loss may recur several times throughout your life. Alopecia areata is more likely to happen if you have other family members with this condition. Telogen effluvium is a type of hair loss where the body undergoes emotional or physical stress which causes all of your hair to enter telogen phase simultaneously, rather than in its normal pattern. Some causes of this stress include deaths in the family, extreme diets, and illnesses. Generally, this condition will revert back to normal hair growth, but this takes many months to happen. There is also a condition called anagen effluvium, where hair in the growing phase is lost usually due to chemotherapy treatment. Hair generally re-grows a little while after chemotherapy has ended but may not be as thick as previously. Traction alopecia is the type of hair loss that results from pulling the hair. Wearing the hair too tightly (as is seen with tight braids) or too much hairstyling can cause this type of hair loss. This type of hair loss most commonly occurs between the rows of braids or at the part of hair. If recognized and stopped early, you can prevent scarring to your scalp that causes permanent hair loss. Other causes of hair loss include poor diet and nutrition, medications, diseases, hormone changes, hair treatments, infections of the scalp, and obsessive pulling of the hair (trichotillomania).

SYMPTOMS
Hair loss either in patches or diffusely over the scalp, itching of the scalp, pain of the scalp, hair loss in the facial hair or body hair

DIAGNOSIS
Your doctor will take a careful history and physical exam. He or she will look at your scalp to see the pattern of your hair loss and any signs of infection or other diseases. Your doctor or dermatologist may do a hair-pull test where about 10 hairs are pulled from the head to determine their hair growth stage by looking at them under a microscope. This test is extremely important to diagnosis conditions like telogen effluvium, where most of the hairs will be in telogen stage. Skin scrapings may be taken to rule out infection as the cause of your hair loss. Sometimes a biopsy (small sample) of your skin may need to be taken to look for alopecia areata or cicatricial alopecia. Your doctor or dermatologist will want to rule out many other medical causes of your hair loss which may involve taking blood samples for testing.

TREATMENT
Many treatments are available when hair loss is ongoing but once it is gone, it is much more difficult to treat. Some types of hair loss, like telogen and anagen effluvium, will begin to regrow hair without any medical intervention. Other types of alopecia can require medical treatement. One medication option is minoxidil (Rogaine) which comes in a liquid or foam form that you rub in to your scalp to promote new hair growth. The hair that is grown with minoxidil may be a little shorter and thinner than normal hair, but may be able to cover bald spots. Finasteride ( Propecia) is a prescription medication available for men which is taken by mouth which helps decrease the rate of hair loss. Finasteride works by preventing the conversion of testosterone to dihydrotestosterone (DHT) which causes follicles to shrink and increases hair loss. Finasteride cannot be taken by women because of the high risk of birth defects. With both minoxidil and finasteride, you need to continue taking these medications to continue reaping the benefit of the therapy. In some cases, like alopecia areata, corticosteroids, either by mouth or via injections into the scalp, may also be helpful. Another medication option is anthralin (Dithro-Scalp) which is a tarry cream or ointment applied to the scalp and washed off daily which may help with alopecia areata. In addition to medications, a few surgical options also exist for treatment of alopecia. Hair transplant can be done with small grafts of various types where tiny plugs of hair-containing skin are harvested from the hair-rich areas of our scalp and transplanted to the bald areas. Another surgical option is a scalp reduction which involves removing part of the scalp which is bald and stretching the existing scalp with hair forward. Discussing all of your options with your doctor and dermatologist is a smart idea before proceeding with any treatment or procedure. As an alternative to medications and surgeries, You can also use wigs or hairpieces to cover areas of your scalp which may be losing hair. Options for hairpieces or wigs are extensive and some are very high-quality. If you are coping with hair loss, it is important to have support from those around you. You can be proactive by learning about your condition and treatment options and educating the people close to you. Things you can do to help minimize your hair loss when you are faced with thinning hair include eating a healthy diet, handling your hair carefully, not putting hair in tight braids or pulled back tightly, and not playing with hair by twisting or pulling it. You may also consider joining a support group for support coping with hair loss.

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