Active clinical trials for Obstetrics & Gynecology:

TITLE DESCRIPTION
Blood Loss during fibroid surgery Use of Intravenous Tranexamic Acid during Myomectomy: A Randomized Double-Blind Placebo Controlled Trial The goal of this study is to help us learn more about the ability of a drug called tranexamic acid to reduce blood loss and the need for a blood transfusion that occurs during a myomectomy (fibroid surgery). Tranexamic acid is approved for patients undergoing cardiac, knee and hip surgery by the FDA but yet not approved for the indication of myomectomy surgery as being investigated in this study. The research team would like to enroll healthy women between 18 and 50 years of age; with no history of blood clots in the legs or lungs, heart attack, stroke or kidney disease and scheduled for an abdominal, laparoscopic or robotic myomectomy at George Washington University Hospital.
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Fetal Vasoreactivity in normal pregnancy This study is being performed at Children's National Health System. We are trying to understand how the normal fetus controls blood flow to the different parts of the body such as the lungs and brain. We will measure your baby’s blood flow using the same ultrasound approach used by your obstetrician. We will test your baby’s control of blood flow by measuring the responses to changes in your (the mom’s), levels of oxygen and carbon dioxide. We will make these changes by asking you to breathe extra oxygen for short periods of time. If your obstetrician determines that your pregnancy is uncomplicated, you and your baby are eligible for this study.
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Sonography-Guided Transcervical Ablation of Uterine Fibroids (SONATA) [This study is no longer recruiting.] The SONATA Study is an FDA-approved clinical study designed to establish the safety and effectiveness of a new, investigational device to reduce heavy menstrual bleeding caused by uterine fibroids. The device, called the SONATA System, targets fibroids rather than treatment or removing the entire uterus. If effective, this device will provide an alternative to hysterectomy that is: incision-free, preserves the uterus, does not require general anesthesia and is an outpatient procedure.
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