Controlled Trial of Deep Brain Stimulation (DBS) for Obsessive Compulsive Disorder (OCD)

The goal of this study is to complete the first definitive controlled trial of a neurosurgical procedure for a severe psychiatric illness. The study will compare the effects of three months of double-masked placebo versus active DBS on OCD severity. Potential participants must: -be between the ages of 18 and 75 -have OCD diagnosed by Structured Clinical Interview for DSM-IV (SCID-IV) -have persistence of sever symptoms and impairment for five years or more despite at least three first-line and two second-line treatments.

Primary Sponsor:
National Institutes of Health (NIH)

Prinicipal Investigator:
Donald Shields, MD

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