Prevention of Postpartum Hemorrhage: Pharmacokinetics and Pharmacodynamics of Tranexamic Acid

Tranexamic acid was shown to significantly reduce risk of mortality when given to women with diagnosed postpartum hemorrhage in the recent Lancet WOMAN Trial.* The purpose of this study is to determine the optimal dose for using tranexamic acid to prevent postpartum hemorrhage during routine cesarean section. Women must be at risk for postpartum hemorrhage to enroll and must not have a history of blood clots or a known clotting condition. *http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31111-X/fulltext

Primary Sponsor:
NIH/CTSI KL2 Grant

Prinicipal Investigator:
Dr. Homa Ahmadzia/OB GYN

Contact Phone:
202-741-2592

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