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We are looking to see if Tradjenta, an FDA Approved Type 2 Diabetes medication, can help improve kidney function and cardiovascular health. We are looking for patients aged 40-70 years with Type 2 Diabetes who are taking Metformin, Insulin, or BOTH Insulin and Metformin. Your HbA1C should be between 6.5 ‚Äì 10 %.