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Infectious Diseases

Treatment for HIV, Aids, Fungal Infections & More

Our doctors in the Infectious Diseases Outpatient Clinic at The GW Medical Faculty Associates provide diagnostic evaluation and treatment for patients with suspected infectious diseases, including chronic illnesses such as osteomyelitis, HIV/AIDS, immune deficiencies, tuberculosis, and fungal infections.

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Clinical Trials

  • A phase 1, randomized, double-blind, placebo-controlled dosage escalation trial to evaluate the safety and immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted in HIV-uninfected, healthy adult volunteers
    This is a phase 1 first-in-human clinical trial to assess the safety, tolerability, and immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted, in up to 48 healthy adult HIV-negative volunteers.
  • Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-acting Cabotegravir Plus Long-acting Rilpivirine From Current Antiretroviral Regimen in Virologically Suppressed HIV-1-infected Adults
    The Antiretroviral Therapy as Long Acting Suppression (ATLAS) study is being conducted to establish if human immunodeficiency virus type-1 (HIV-1) infected adult participants with current viral suppression on a regimen with 2 nucleoside reverse transcriptase inhibitors (NRTIs) plus a third agent, remain suppressed upon switching to a two-drug intramuscular (IM) long-acting (LA) regimen of cabotegravir (CAB) and rilpivirine (RPV). This is a Phase 3, multi-phase, randomized, open label, active-controlled, multicenter, parallel-group, non-inferiority study in HIV-1, antiretroviral therapy (ART)-adult participants who are stably suppressed on a current antiretroviral (ARV) regimen. This study is designed to demonstrate the non-inferior antiviral activity of switching to a two drug CAB LA 400 mg + RPV LA 600 mg regimen every 4 weeks (Q4W: monthly) compared with maintenance of current ARV regimen containing 2 NRTIs plus an INI, NNRTI, or a PI. Eligible participants will be randomized (1:1) i
  • Efficacy of Hookworm Vaccine Assessed by Controlled Challenge Infection
    This is a 14-month, randomized, Phase 2 clinical study comparing the impact of Na-GST-1 vaccination on controlled human hookworm infection in healthy volunteers. Participants will receive 3 injections of the investigational hookworm vaccine (or placebo), followed by infection with 50 human hookworm larvae.
  • A Hookworm Infection Study in Healthy Adults
    This study is being conducted to determine the optimal dose of infectious hookworm larvae that is safe to give to healthy adults, and that leads to an infection with adult worms in the intestine. Hookworm is a parasitic worm that can live for several years in the intestine of humans, feeding on the blood of the people they infect. Study participants will provide routine stool and blood samples and will receive anti-worm medication 3 months from application of the larvae to treat the infection. This study is looking to enroll males or females, 18-45 years of age in good general health, who are available for the duration of the study (6 months). Subjects must be HIV, Hep-B and Hep-C negative.